Laboratory Specialty Services
Medchemexpress LLC Compound E | 209986-17-4 | 99.97% | C27H24F2N4O3 | 1 ML
Compound E is a γ-secretase inhibitor. It blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage, making it suitable for various research applications.
- Blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage
- Inhibits gamma secretase-mediated amyloid beta (1 to 40) production
- Reduces proliferation of T47D and MCF-7 cell lines
Hampton Research HR2-931-13/StockOptions Sodium HEPES #13 pH 8.0, 185 ml
HR2-931-13/StockOptions Sodium HEPES #13 pH 8.0, 185 ml. Please note items from this supplier are non-returnable.
Hampton Research HR2-939-19/StockOptions Sodium Cacodylate #19 pH 6.9, 185 ml
HR2-939-19/StockOptions Sodium Cacodylate #19 pH 6.9, 185 ml. Please note items from this supplier are non-returnable.
![Medchemexpress LLC Benzamide, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)- | 1020149-73-8 | 99.8% | 461.52 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000366152-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzamide, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)- | 1020149-73-8 | 99.8% | 461.52 | 50 MG
SGI-1027 is a potent DNA methyltransferase (DNMT) inhibitor. It targets DNMT3B, DNMT3A, and DNMT1, exhibiting selective degradation of DNMT1 in various human cancer cell lines. The compound shows minimal cytotoxicity in rat hepatoma cells and does not induce apoptosis in these cells, while demonstrating antiproliferative activity and cytotoxicity against several human cell lines.
- DNA methyltransferase (DNMT) inhibitor
- Targets DNMT3B, DNMT3A, and DNMT1
- Selectively degrades DNMT1 in human cancer cell lines
- Low cytotoxicity in rat hepatoma cells
- Does not induce apoptosis in rat hepatoma cells
- Exhibits antiproliferative activity and cytotoxicity against various human cell lines
Hampton Research MEMBFAC NO04 185ML
HR2-920-04/MembFac #04 (A4), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium acetate trihydrate pH 4.6, 12% v/v 2-Propanol. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO06 185ML
HR2-920-06/MembFac #06 (A6), 185 ml - 0.1 M Sodium acetate trihydrate pH 4.6, 1.0 M Ammonium sulfate. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO12 185ML
HR2-920-12/MembFac #12 (A12), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 18% v/v Polyethylene glycol 400. Please note items from this supplier are non-returnable.
Hampton Research NATRIX NO48 185ML
HR2-918-48/Natrix #48 (D12), 185 ml - 0.2 M Ammonium chloride, 0.01 M Calcium chloride dihydrate, 0.05 M TRIS hydrochloride pH 8.5, 30 % w/v Polyethylene glycol 4,000. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO30 185ML
HR2-920-30/MembFac #30 (C6), 185 ml - 0.1 M Sodium chloride, 0.1 M HEPES sodium pH 7.5, 10% w/v Polyethylene glycol 4,000. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO15 185ML
HR2-920-15/MembFac #15 (B3), 185 ml - 0.1 M Sodium chloride, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 12% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.
Hampton Research MEMBFAC NO22 185ML
HR2-920-22/MembFac #22 (B10), 185 ml - 0.1 M ADA pH 6.5, 1.0 M Ammonium sulfate. Please note items from this supplier are non-returnable.
Hampton Research HR2-944-32/Index #32 (C8), 185 ml - 1.0 M Ammonium sulfate, 0.1 M BIS-TRIS pH 5.5, 1% w/v Polyethylene glycol 3,350
HR2-944-32/Index #32 (C8), 185 ml - 1.0 M Ammonium sulfate, 0.1 M BIS-TRIS pH 5.5, 1% w/v Polyethylene glycol 3,350. Please note items from this supplier are non-returnable.
Aqua Solutions Solvent Mix: 40% Acetone 40% Acetic Acid, 20% Chloroform v/v (4L)
Solvent Mix: 40% Acetone 40% Acetic Acid, 20% Chloroform v/v (4L)
Hampton Research MEMBFAC NO35 185ML
HR2-920-35/MembFac #35 (C11), 185 ml - 0.1 M Sodium citrate tribasic dihydrate, 0.1 M HEPES sodium pH 7.5, 12% v/v (+/-)-2-Methyl-2,4-pentanediol. Please note items from this supplier are non-returnable.